The ADVIA® 2400 Clinical Chemistry System manages the most demanding workloads and meets high turnaround-time (TAT) goals. Its menu includes methods for testing drugs-of-abuse, therapeutic drugs (TDM) and new assays such as cystatin C and CardioPhase® hsCRP. The ADVIA 2400 Clinical Chemistry System offers:
- High throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage heavy workloads
- Rapid, consistent, 2-second cycle time for faster tube speed and test throughput
- User-defined automatic repeat, dilution, and reflex testing
- Large onboard reagent capacity and optional concentrated reagents help to minimize intervention demands
- Refrigerated onboard storage of controls and reagents for extended stability and increased productivity
- Automation-ready design: no additional hardware required
Features & Benefits
The ADVIA 2400 Clinical Chemistry System meets today’s high turnaround-time goals with a throughput of up to 2400 tests/hour. In addition to assays for general and specialty chemistries, its menu includes assays for specific protein measurement, drugs-of-abuse testing (DAT), and therapeutic drug monitoring (TDM). Interesting new assays such as cystatin C, HbA1c with automated sample pretreatment, and CardioPhase® hsCRP can now be included in your routine testing.
The ADVIA 2400 Chemistry System pushes productivity levels while maintaining the reliability and stability that keep laboratories up and running. A rapid, 2-second probe cycle time maximizes tube speed and test throughput and combines with the system’s efficient automation-readiness to provide the turnaround time needed for high-volume laboratories
Superior Speed and Productivity
- Throughput of up to 2400 tests/hour (1800 photometric and 600 ISE) to manage the heaviest workloads
- Rapid, consistent, 2-second cycle time
- Throughput of 200 tubes per hour, even when running three ISE tests and nine photometric tests per sample
- Automatic Sample Retain technology, auto-repeat, auto-dilution, and auto-reflex testing
Automation-ready
- Point-in-space aspiration enables connectivity to a track.
- Redundant sample loading provides built-in backup and easy handling of non-routine samples.
- Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting.
Minimal Need for Operator Intervention
- Minimal-maintenance ISEs
- Large onboard reagent capacity and optional concentrated reagents for fewer interruptions
- No-maintenance, 37°C incubation oil bath
- Auto-calibration and auto-QC from refrigerated onboard calibrators and controls
- Microvolume technology with 32,000 tests onboard and up to 60 days’ onboard stability for improved walkaway time. Concentrated reagents for increased maximum capacity.
- Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options
Exceptional Reliability
- Sample integrity check for icterus, hemolysis, and lipemia
- Sample probe with automatic clot/clog detection, liquid-level sensing, short-sample detection, and crash protection
- Advances in onboard reagent stability, calibration frequency, reduction in interferences, and expanded assay linearity
Technical Specifications
Overview |
|
Type of System |
Random, continuous access, batch, discrete processing |
Throughput Rate |
Up to 2400 tests/hour: 1800 tests/hour colorimetric, 600 tests/hour ISE |
Onboard Assays Capacity |
49, including 3 ISE |
Sample Handling |
|
Sample Tubes |
5 mL, 7 mL, 10 mL, 2 mL sample cups |
Sample Tray |
84 samples, positive sample identification |
Bar Codes |
Interleaved 2 of 5, code 39, code 128, Codabar (NW7) |
STAT Sample Loading |
84, not dedicated |
Auto-repeat |
Automatic repeat testing from the retained pre-diluted sample |
Auto-dilution |
Automatic dilution from retained pre-diluted sample |
Auto-reflex Testing |
Automatic ability to perform three additional tests based on results of first test |
Primary Probe |
Liquid Level Sensing, Crash Protection, Clot/Clog Detection, Short Sample Detection |
Sample Integrity Check |
Qualitative check for hemolysis, lipemia and icterus |
Microvolume Technology |
|
Automatic Sample Predilution |
Samples diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 test results), retained for auto-repeat until results are available |
Predilution Tray |
120 dilution cuvettes |
Original Sample Volume |
2–30 µL; system uses an average of 2–3 µL per test |
Average Reagent Volume |
80–120 µL per test |
Onboard Storage Capacity |
20,000 tests average; use of concentrated reagents increases maximum capacity |
Reaction Area |
|
Reaction Tray |
340 reusable plastic cuvettes |
Cuvette Optical Path Length |
6 mm |
Reaction Bath |
Inert fluorocarbon oil circulation system, 37°C |
Photometer |
14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm) |
Light Source |
12 V, 50 W halogen lamp, cooled by forced water circulation |
Assay Methods |
Endpoint, rate reaction, 2-point rate, multi-point homogeneous immunoassay |
Reaction Times |
3, 4, 5, 10, 15 and 21 minutes |
Automatic Correction |
Serum blank, cell blank, measurement point change, sample volume change in re-assay |
Point Forwarding |
Automatically extends linerarity over assay range samples |
Reagent Handling |
|
Reagent Tray |
Two trays, 50 positions each, refrigerated |
Reagent Capacity Onboard |
46 colorimetric methods |
Dispensing System |
Two probes with liquid-level sensing and liquid surface verification |
Reagent Wedges |
20, 40 and 70 ml bar-code-labeled wedges |
Onboard Stability |
Up to 60 days |
Reagent Inventory Management |
Tracks tests remaining, lot number, onboard stability and expiration date |
Reagent Dilutions |
Capability to dilute concentrated reagents onboard |
Open System Capability |
|
Channels |
200 channels, includes user-defined applications |
Third-party Applications |
Varies by country, can be configured on system |
ISE |
|
ISE |
Indirect simultaneous measurement of Na+, K+, Cl- |
Sample Volume |
22 µL for all three tests |
Priming |
Automatic priming cycle |
Electrode Life |
30,000 samples or 3 months |
Throughput Rate |
600 tests/hour; 200 tubes/hour |
Calibration/QC |
|
Calibration Interval |
Up to 60 days, tracked by software |
Auto-Calibration/Auto-QC |
User-defined time interval or with new reagent wedge |
View Calibration/QC Data |
Graphical display of calibration curve and QC; Smart Remote Services QC monitoring |
Calibration/Control Tray |
61 refrigerated positions for calibrators, controls and diluents |
Data Management |
|
Operating Computer |
WINDOWS XP, flat-panel display |
System |
Operator manual and assays sheets online |
Host Interface |
RS 232C bidirectional |
Data Storage |
70,000 patient samples |
Onboard |
Schedule and monitor routine maintenance activities via software |
Host Query |
ASCII; system requests work order or batch of work orders from host |
General Specifications |
|
Power Requirements |
100/115/200/220/230/240 V ± 10%, 30 A, 50/60 Hz, 3 KVA |
Water Requirements |
Deionized water |
Maximum Water Consumption |
40 liters per hour |
Drain requirements |
Minimum of 10.6 gallons (40 liters) per hour |
Dimensions |
52.8 (h) x 67.4 (w) x 34.1 (d) in., 134 (h) x 171.1 (w) x 86.7 (d) cm |
Weight |
1,389 lb (630 kg) |
Compliance |
cUL, CSA, CE |
Noise Specifications |
Open cover: less than 70 db, closed cover: less than 45 db |
Average Heat Output |
5374 BTU/hour |
Operating Temperature Range |
18–30°C/64–86°F |
Ambient Humidity |
40–70% |