The ADVIA® 1800 Clinical Chemistry System pushes the limit of productivity. Its extensive menu allows integration of testing for clinical chemistry, drugs-of-abuse, therapeutic drug monitoring (TDM) and specific proteins such as cystatin C and CardioPhase® hsCRP. The ADVIA 1800 Clinical Chemistry System offers:
- Throughput of up to 1,800 tests per hour to keep pace with workload peaks
- 200 basic metabolic panels per hour to meet turnaround-time demands
- Large onboard reagent capacity and optional concentrated reagents to reduce interruptions
- Optimal standardization of reagents and systems for efficient consumable usage
- Refrigerated onboard storage of controls and reagents for extended stability and increased productivity
- Automation-ready design: no additional hardware required
Features & Benefits
The ADVIA 1800® Clinical Chemistry System pushes the limit of productivity in the core lab and meets the turnaround-time (TAT) goals of today’s laboratories. Its extensive menu allows integration of general clinical chemistry testing with testing for drugs-of-abuse, TDM, special chemistry, and specific proteins such as cystatin C and CardioPhase® hsCRP.

Automation-ready design
- Point-in-space aspiration enables connectivity to a track, VersaCell® System.
- Redundant sample loading provides built-in backup and easy handling of non-routine samples.
- Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting.
Peak productivity
- Throughput of up to 1,800 tests per hour provides the speed to keep pace with workload peaks.
- Throughput of 200 basic metabolic panels per hour helps to meet turnaround-time demands.
- Automatic Sample Retain technology lets you perform reruns and dilutions without the need to retrieve primary tubes.
- Consolidate chemistry testing on one system with a comprehensive menu, consistent cycle times, speed, and open application capability.
Total system reliability
- Minimal-maintenance ISEs
- Robust hardware and simplified software design, with automatic calibration validation and tracking
- Advances in reagent onboard stability, calibration frequency, interference reduction and assay linearity expansion
- Direct water connection
- Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options
Easy efficiency
- Large onboard reagent capacity and optional concentrated reagents reduce interruptions.
- High-resolution touchscreen delivers push-button operation.
- Reagent pause capability and onboard Sample Pause button make loading easy.
- Minimal maintenance requirements, including no-maintenance oil bath, reduce hands-on time.
- Sample integrity checking, include serum indices reporting, short-sample flagging, and clot detection, reducing the need for manual intervention.
Technical Specifications
Overview |
|
Type of System |
Random, continuous access, batch, discrete processing |
Throughput Rate |
Up to 1800 tests/hour: 1200 tests/hour colorimetric, 600 tests/hour ISE |
Onboard Assay Capacity |
55, including 3 ISE |
Sample Handling |
|
Sample Tubes |
5 mL, 7 mL, 10 mL tubes, 2 mL sample cups |
Sample Tray |
84 samples, positive sample identification |
Sample Integrity Check |
Qualitative check for hemolysis, lipemia, and icterus |
STAT Sample Loading |
84, not dedicated |
Bar Codes |
Interleaved 2 of 5, Code 39, Code 128, Codabar (NW7) |
Auto-repeat |
Automatic repeat testing from the retained prediluted sample or original sample |
Auto-dilution |
Automatic dilution from retained prediluted sample |
Auto-reflex Testing |
Automatic ability to perform three additional tests based on results of first test |
Primary Probe |
Liquid-level sensing, crash protection, clot/clog detection, short-sample detection |
Microvolume Technology |
|
Automatic Sample Predilution |
Samples diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests), retained for auto-repeat until results are available |
Predilution Tray |
120 dilution cuvettes |
Original Sample Volume |
2-30 μL; average of 2-3 μL per test |
Average Reagent Volume |
80-120 μL per test |
Onboard Storage Capacity |
25,200 tests average; usage of concentrated reagents increases maximum capacity |
Reaction Area |
|
Reaction Tray |
221 reusable plastic cuvettes |
Cuvette Optical Path Length |
10 mm |
Reaction Bath |
Inert fluorocarbon oil circulation system, 37°C |
Photometer |
14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm) |
Light Source |
12 V, 50 W halogen lamp, cooled by forced water circulation |
Assay Methods |
Endpoint, rate reaction, 2-point rate, multipoint homogeneous immunoassay |
Reaction Times |
3, 4, 5, 10, 15, and 21 minutes |
Automatic Correction |
Serum blank, cell blank, measurement point change, sample volume change in reassay |
Point Forwarding |
Automatically extends linearity over assay range samples |
Reagent Handling |
|
Reagent Tray |
2 trays, 56 positions each, refrigerated |
Reagent Capacity Onboard |
52 colorimetric methods |
Dispensing System |
Two probes with Liquid Level Sensing and Liquid Surface Verification |
Reagent Wedges |
20, 40, 70 mL bar-code-labeled wedges |
Reagent Inventory Management |
Tracks tests remaining, lot number, onboard stability, and expiration date |
Reagent Dilutions |
Capability to dilute concentrated reagents onboard |
Open System Capability |
|
Channels |
200 channels, includes user-defined applications |
3rd Party Applications |
Varies by country, can be configured on system |
ISE |
|
ISE |
Indirect simultaneous measurement of Na+, K+, Cl – |
Sample Volume |
22 μL for all three tests |
Priming |
Automatic priming cycle |
Electrode Shelf Life |
30,000 samples or 3 months |
Throughput Rate |
600 tests/hour; 200 tubes/hour |
Calibration/QC |
|
Calibration Interval |
Up to 60 days, tracked by software |
Auto-calibration/Auto-QC |
User-defined time interval or with new reagent container |
View Calibration/QC Data |
Graphical display of calibration curves and QC; Siemens Remote Services QC monitoring |
Calibration/Control Tray |
61 refrigerated positions for calibrators, controls, and diluents |
Data Management |
|
Operating Computer |
WINDOWS XP, 1 GB RAM, 19-inch touchscreen monitor |
System Documentation |
Operator manual and assay sheets online |
Host Interface |
RS 232C bidirectional |
Data Storage |
70,000 patient tests |
Onboard Maintenance Logs |
Schedule and monitor routine maintenance activities via software |
Host Query |
ASCII; system requests work order or batch of work orders from host |
General Specifications |
|
Power Requirements |
200/220/230/240 V ± 10%, 20 A, 50/60 Hz, 3 KVA |
Water Requirements |
Deionized water from pressurized water (10-30 psi/169-207 KPa) Average consumption: 30 liters per hour |
Drain Requirements |
Minimum of 40 liters per hour |
Dimensions |
44.6 (h) x 58.3 (w) x 34.5 (d) in, 113.3 (h) x 148.0 (w) x 87.6 (d) cm |
Weight |
1,323 lb (600 kg) |
Compliance |
UL, cUL, CE |
Noise Specifications |
Less than 70 db with cover open |
Average Heat Output |
4,299 BTU/hour @ 50 Hz, 3,023 BTU/hour @ 60 Hz |
Operating Temperature Range |
18°-30°C/64°-86°F |
Ambient Humidity |
40-70% |